5-Amino-1MQ (5-Amino-1-methylquinolinium) is a potent, small-molecule selective inhibitor of nicotinamide N-methyltransferase (NNMT). NNMT is the enzyme responsible for methylating nicotinamide (vitamin B3) into 1-methylnicotinamide, a process that can deplete cellular NAD+ levels.
By inhibiting NNMT, 5-Amino-1MQ helps preserve and elevate intracellular NAD+ levels, supporting sirtuin activity, mitochondrial function, and cellular energy metabolism. It is widely used in research exploring metabolic regulation, NAD+ biosynthesis, sirtuin-dependent pathways, and age-related cellular decline.
**Research Applications:**
– Modulation of NAD+/NADH ratios
– Sirtuin activation and deacetylation pathways
– Mitochondrial oxidative phosphorylation
– NNMT enzyme kinetics and metabolic studies
**Specifications:**
– Quantity: 10 mg
– Form: Lyophilized powder
– Purity: >99% (HPLC verified)
**Intended Use:**
For research purposes only. Strictly for *in vitro* laboratory use. Not for human consumption, veterinary use, or any diagnostic purpose. This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease. All sales are final. The buyer assumes full responsibility for proper handling, storage, and regulatory compliance.
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